Smiths Station is a city in Lee County, Alabama, United States.The city is a part of the Columbus, Georgia-Phenix City, Alabama Metropolitan Statistical Area. The city is also known by locals as "Smiths", although the official name is "Smiths Station". At the time of the 2000 census, it was still a census-designated place, and its population was 21,756. The area that incorporated as Smiths Station in 2001 was much smaller than the CDP, and contained a population of 4,926 according to the 2010 census. Smiths Station is a bedroom community of Columbus, Georgia and Phenix City, Alabama. Smiths Station High School has an enrollment of 1,800+ students and is the 11th largest high school in the state.